<p class="ql-align-justify">A Body Shape Index (ABSI) is a new adiposity metric that has been linked with chronic metabolic diseases such as diabetes mellitus, type 2, cardiovascular diseases, and cancer risk in some studies. ABSI is an anthropometric index that takes into account waist circumference (WC), body mass index (BMI), and height. The aim of this study was to determine the relationship of ABSI with clinical and biochemical indices in undergraduates. This cross-sectional study involved 97 undergraduate students of Edo State University Uzairue, Edo State, Nigeria (16–26 years old). They comprised 65 females and 32 males. Information on socio-demography was obtained from administered semi-pretest questionnaire. Anthropometric indices; body weight, height, waist circumference, hip circumference and mid-upper arm circumference were determined using standard methods. BMI, ABSI, waist hip ratio and waist height ratio were calculated. Blood pressure, pulse rate, pulse pressure, saturation of peripheral oxygen (SPO₂), and body composition including lean body mass, body water, metabolism and so on. as well as plasma glucose and total cholesterol were determined by standard methods. Age, body weight, height, mid-upper arm circumference, systolic blood pressure, lean body mass, metabolism were significantly higher in males, while body age, SPO₂&nbsp;and fat were significantly higher in females than males (p&lt;0.05). ABSI positively correlated with height, waist circumference, pulse rate, visceral fat, metabolism, and lean body mass (p&lt;0.05). Observations in this study show that ABSI could be a good index of assessing abdominal obesity, hence, its recommendation for obesity screening in studies is suggested.</p><p><br></p>